Weigmann B (2014)
Publication Type: Journal article
Publication year: 2014
Publisher: Humana Press, Inc.
Book Volume: 1193
Pages Range: 143-51
DOI: 10.1007/978-1-4939-1212-4_14
Animal model of intestinal inflammation is essential for the understanding of the pathomechanisms of inflammatory bowel diseases like Crohn's disease and ulcerative colitis. Typically, naïve T-cells were transferred into immunocompromised mice and develop gut inflammation because of inappropriate downregulation. Here, we describe the isolation, purification, and transfer of CD4(+)CD25(-) T-cells into recipients to obtain an experimental colitis model for the analysis of pathogenesis.
APA:
Weigmann, B. (2014). Induction of colitis in mice (T-cell transfer model). Methods in Molecular Biology, 1193, 143-51. https://doi.org/10.1007/978-1-4939-1212-4_14
MLA:
Weigmann, Benno. "Induction of colitis in mice (T-cell transfer model)." Methods in Molecular Biology 1193 (2014): 143-51.
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