Tuning of Cell-Biomaterial Anchorage for Tissue Regeneration
Leal-Egaña A, Diaz-Cuenca A, Boccaccini AR (2013)
Publication Type: Journal article
Publication year: 2013
Journal
Publisher: Wiley-VCH Verlag
Pages Range: 4049-4057, DOI
Journal Issue: 25(29)
Abstract
Which mechanisms mediate cell attachment to biomaterials? What role does the surface charge or wettability play on cell-material anchorage? What are the currently investigated strategies to modify cell-matrix adherence spatiotemporally? Considering the development of scaffolds made of biocompatible materials to temporarily replace the structure and/or function of the extracellular matrix, focus is given to the analysis of the specific (i.e., cell adhesive peptide sequences) and unspecific (i.e., surface charge, wettability) mechanisms mediating cell-matrix interactions. Furthermore, because natural tissue regeneration is characterized by the dynamic attachment/detachment of different cell populations, the design of advanced scaffolds for tissue engineering, based in the spatiotemporal tuning of cell-matrix anchorage is discussed. Focus is given on the analysis of the specific and unspecific mechanisms mediating cell-matrix interactions. Furthermore, because natural tissue regeneration is characterized by the dynamic attachment/detachment of different cell populations, the advanced design of scaffolds for tissue engineering, based in the spatiotemporal tuning of cell-matrix anchorage, is discussed. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Authors with CRIS profile
Involved external institutions
Spain (ES)How to cite
APA:
Leal-Egaña, A., Diaz-Cuenca, A., & Boccaccini, A.R. (2013). Tuning of Cell-Biomaterial Anchorage for Tissue Regeneration. Advanced Materials, 25(29), 4049-4057, DOI. https://doi.org/10.1002/adma.201301227
MLA:
Leal-Egaña, Aldo, Aranzazu Diaz-Cuenca, and Aldo R. Boccaccini. "Tuning of Cell-Biomaterial Anchorage for Tissue Regeneration." Advanced Materials 25(29) (2013): 4049-4057, DOI.
BibTeX: Download