Olalde B, Garmendia N, Saez-Martinez V, Argarate N, Nooeaid P, Morin F, Boccaccini AR (2013)
Publication Type: Journal article
Publication year: 2013
Publisher: Elsevier
Pages Range: 3760-3767
Journal Issue: 33(7)
DOI: 10.1016/j.msec.2013.05.002
A new family of multifunctional scaffolds, incorporating selected biopolymer coatings on basic Bioglass® derived foams has been developed. The polymer coatings were investigated as carrier of vancomycin which is a suitable drug to impart antibiotic function to the scaffolds. It has been proved that coating with PLGA (poly(lactic-co-glycolic acid)) with dispersed vancomycin-loaded microgels provides a rapid delivery of drug to give antibacterial effects at the wound site and a further sustained release to aid mid to long-term healing. Furthermore, the microgels also improved the bioactivity of the scaffolds by acting as nucleation sites for the formation of HA crystals in simulated body fluid. © 2013 Elsevier B.V.
APA:
Olalde, B., Garmendia, N., Saez-Martinez, V., Argarate, N., Nooeaid, P., Morin, F., & Boccaccini, A.R. (2013). Multifunctional bioactive glass scaffolds coated with layers of poly(d,l-lactide-co-glycolide) and poly(n-isopropylacrylamide-co-acrylic acid) microgels loaded with vancomycin. Materials Science and Engineering C, 33(7), 3760-3767. https://doi.org/10.1016/j.msec.2013.05.002
MLA:
Olalde, B., et al. "Multifunctional bioactive glass scaffolds coated with layers of poly(d,l-lactide-co-glycolide) and poly(n-isopropylacrylamide-co-acrylic acid) microgels loaded with vancomycin." Materials Science and Engineering C 33(7) (2013): 3760-3767.
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