Beauchamp J, Kirsch F, Büttner A (2010)
Publication Type: Journal article
Publication year: 2010
Publisher: Institute of Physics: Hybrid Open Access
Book Volume: 4
Pages Range: 1-12
Journal Issue: 026006
DOI: 10.1088/1752-7155/4/2/026006
Eucalyptol (1,8-cineole) is a common active agent in non-prescription pharmaceutical products that is employed to clear the airways during mucus blockages. Following ingestion of a eucalyptol-containing capsule, the capsule dissolves in the gut and transfers eucalyptol into the blood, which is subsequently expelled via the lungs, thus exposing this decongesting and inflammation-abating compound to the airways. The breath gas concentrations of eucalyptol in 11 healthy adult volunteers were monitored at regular intervals after capsule ingestion using on-line proton-transfer-reaction mass spectrometry (PTR-MS). Eucalyptol appeared in exhaled breath gas at varying times following ingestion, with its onset ranging from 1 h and 6 min to 4 h and 48 min (mean ± SD: 2.1 ± 0.5 h). Maximum concentrations also varied greatly, with peak eucalyptol levels between 106 and 1589 ppb
APA:
Beauchamp, J., Kirsch, F., & Büttner, A. (2010). Real-time breath gas analysis for pharmacokinetics: monitoring exhaled breath by on-line proton-transfer-reaction mass spectrometry after ingestion of eucalyptol-containing capsules. Journal of Breath Research, 4(026006), 1-12. https://doi.org/10.1088/1752-7155/4/2/026006
MLA:
Beauchamp, Jonathan, Frauke Kirsch, and Andrea Büttner. "Real-time breath gas analysis for pharmacokinetics: monitoring exhaled breath by on-line proton-transfer-reaction mass spectrometry after ingestion of eucalyptol-containing capsules." Journal of Breath Research 4.026006 (2010): 1-12.
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