Subtype Selective Tetracycline Agonists and their Application for a Two-Stage Regulatory System

Berens C, Löber S, Gmeiner P (2006)

Publication Type: Journal article

Publication year: 2006

Journal

ChemBioChem Wiley-VCH Verlag

Publisher: Wiley-VCH Verlag

Book Volume: 7

Pages Range: 1320-1324

DOI: 10.1002/cbic.200600226

Abstract

We are in control. Rational-based structural modifications of tetracycline derivatives that can act as selective inducers of the transactivating proteins rtTA-1/2 and rtTA-D have been carried out. These modifications led to a novel two-stage regulatory system in which two separate genes can be regulated by using the selective inducers 9-dipropylaminodoxycycline (1) and doxycycline (dox). © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

Authors with CRIS profile

Christian Berens Lehrstuhl für Mikrobiologie Stefan Löber Lehrstuhl für Pharmazeutische Chemie Peter Gmeiner Lehrstuhl für Pharmazeutische Chemie

How to cite

APA:

Berens, C., Löber, S., & Gmeiner, P. (2006). Subtype Selective Tetracycline Agonists and their Application for a Two-Stage Regulatory System. ChemBioChem, 7, 1320-1324. https://doi.org/10.1002/cbic.200600226

MLA:

Berens, Christian, Stefan Löber, and Peter Gmeiner. "Subtype Selective Tetracycline Agonists and their Application for a Two-Stage Regulatory System." ChemBioChem 7 (2006): 1320-1324.

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