Simple methods to fabricate Bioglass (R)-derived glass-ceramic scaffolds exhibiting porosity gradient

Bretcanu O, Samaille C, Boccaccini AR (2008)

Publication Type: Journal article

Publication year: 2008

Journal

Journal of Materials Science Springer Verlag (Germany)

Publisher: Springer Verlag (Germany)

Pages Range: 4127-4134

Journal Issue: 43

DOI: 10.1007/s10853-008-2536-y

Abstract

The present paper discusses different processing technologies for fabrication of novel 45S5 Bioglass®-derived glass-ceramic scaffolds with tailored porosity gradient for potential application in bone tissue engineering. Different types of scaffolds with continuous or stepwise gradient of porosity were produced by the foam replication technique, using preformed polyurethane (PU) foams as sacrificial templates. After preforming the PU foams in metallic moulds, they were dipped in a 45S5 Bioglass ®-based slurry and subsequently heat treated in a chamber furnace up to 1100 °C. During heating, the organic phase is burned out and the glass sinters and partially crystallises. By using this new approach, Bioglass®-derived glass-ceramic scaffolds with different shapes and porosity profiles were designed. Scanning electron microscopy (SEM) showed that all samples have highly interconnected porous structure, with specific porosity gradients. By modifying the shape and dimensions of the metallic mould, bioactive glass-ceramic scaffolds with complex shapes and different degrees of porosity gradient could be obtained. © 2008 Springer Science+Business Media, LLC.

Authors with CRIS profile

Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Imperial College London / The Imperial College of Science, Technology and Medicine GB United Kingdom (GB)

How to cite

APA:

Bretcanu, O., Samaille, C., & Boccaccini, A.R. (2008). Simple methods to fabricate Bioglass (R)-derived glass-ceramic scaffolds exhibiting porosity gradient. Journal of Materials Science, 43, 4127-4134. https://doi.org/10.1007/s10853-008-2536-y

MLA:

Bretcanu, Oana, Claire Samaille, and Aldo R. Boccaccini. "Simple methods to fabricate Bioglass (R)-derived glass-ceramic scaffolds exhibiting porosity gradient." Journal of Materials Science 43 (2008): 4127-4134.

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