Inhibition of calcification of polymer-ceramic composites incorporating nanocrystalline TiO2

Piegat A, El Fray M, Jawad H, Chen QZ, Boccaccini AR (2008)

Publication Type: Journal article

Publication year: 2008

Journal

Advances in Applied Ceramics Maney Publishing

Publisher: Maney Publishing

Pages Range: 287-292

Journal Issue: 107

DOI: 10.1179/174367508X297777

Abstract

An emerging problem related to the development of polymer surfaces resistant to calcification was addressed in this work. Multiblock copolymers containing poly(ethylene terephthalate) (PET) (30 wt-%) as hard segment and dilinoleic acid (DLA) as soft segment were prepared in the presence of two concentrations of TiO2 particles (23 nm diameter) as nanofiller (0·2 and 0·4 wt-%) via in situ polycondensation process. Changes of thermal properties as well as investigations of topography of these nanocomposites suggest that addition of small amount of TiO2 nanoparticles resulted in higher crystallinity and roughness of the copolymer surface. Incubation in simulated body fluid (SBF) increased the roughness of all copolymers characterised by root mean square (rms) values; however, no hydroxyapatite layer was formed on the samples surface. The highest difference of rms values was found for the neat PET/DLA material. The addition of nanocrystalline TiO2 seems to prevent the material surface from calcification which represents a positive effect when such nanocomposite is intended for medical applications, especially for uses in contact with soft tissue. © 2008 Institute of Materials, Minerals and Mining.

Authors with CRIS profile

Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Imperial College London / The Imperial College of Science, Technology and Medicine

United Kingdom (GB) West Pomeranian University of Technology Szczecin / Zachodniopomorski Uniwersytet Technologiczny w Szczecinie (ZUT)

Poland (PL)

How to cite

APA:

Piegat, A., El Fray, M., Jawad, H., Chen, Q.Z., & Boccaccini, A.R. (2008). Inhibition of calcification of polymer-ceramic composites incorporating nanocrystalline TiO2. Advances in Applied Ceramics, 107, 287-292. https://doi.org/10.1179/174367508X297777

MLA:

Piegat, A., et al. "Inhibition of calcification of polymer-ceramic composites incorporating nanocrystalline TiO2." Advances in Applied Ceramics 107 (2008): 287-292.

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