Selective Venous Blood Sampling for Hyperparathyroidism with unclear Localization of the Parathyroid Gland

Hader C, Uder M, Loose RWR, Linnemann U, Bertsch T, Adamus R (2016)

Publication Type: Journal article

Publication year: 2016

Journal

Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren Georg Thieme Verlag

Book Volume: 188

Pages Range: 1144-1150

Journal Issue: 12

DOI: 10.1055/s-0042-113613

Abstract

Purpose: Evaluation of the benefit of selective venous blood sampling (SVS) for the preoperative identification of parathyroid adenomas with unclear localization in non-invasive diagnostics. Materials and Methods: In a retrospective study, all patients (n = 23) with primary (n = 21) or tertiary (n = 2) hyperparathyroidism were evaluated from 2005 to 2016 at the Hospital Nuremberg-North. These patients all received one (n = 20) or more (n = 3) SVS. 15 patients had one or more previous unsuccessful surgeries (group A), 8 patients received the SVS primarily before the first surgery (group B). Results of SVS were compared with the results of surgery, non-invasive diagnostic procedures and clinical follow up. Results: In 24 out of 26 SVS a significant PTH peak was found. 19 patients underwent surgery after SVS. In 16 of these cases (84 %) the SVS peak was concordant with the intraoperative localization. Thus, SVS of all operated patients had a sensitivity of 94 %. Considering only patients with prior HPT surgery the sensitivity was 89 %. In none of the 26 examinations complications occurred. Conclusion: Our results demonstrate that selective venous blood sampling SVS in cases with unclear imaging of parathyroid adenomas is an effective and low-risk invasive diagnostic method to localize parathyroid adenomas and helps to improve surgical therapy. Key points: o?low risk invasive diagnostic procedure to localize parathyroid adenomaso?additional step if non-invasive diagnostics are negative or inconclusiveo?high sensitivity in the detection of parathyroid adenomas Citation Format: o?Hader C, Uder M, Loose RWR et al. Selective Venous Blood Sampling for Hyperparathyroidism with unclear Localization of the Parathyroid Gland. Fortschr Röntgenstr 2016; 188: 1144 - 1150.

Authors with CRIS profile

Christopher Hader Medizinische Fakultät Michael Uder Lehrstuhl für Diagnostische Radiologie

Involved external institutions

Klinikum Nürnberg DE Germany (DE)

How to cite

APA:

Hader, C., Uder, M., Loose, R.W.R., Linnemann, U., Bertsch, T., & Adamus, R. (2016). Selective Venous Blood Sampling for Hyperparathyroidism with unclear Localization of the Parathyroid Gland. Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 188(12), 1144-1150. https://doi.org/10.1055/s-0042-113613

MLA:

Hader, Christopher, et al. "Selective Venous Blood Sampling for Hyperparathyroidism with unclear Localization of the Parathyroid Gland." Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 188.12 (2016): 1144-1150.

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