Short-term outcome of patients with ST-segment elevation myocardial infarction (STEMI) treated with an everolimus-eluting bioresorbable vascular scaffold

Wiebe J, Moellmann H, Most A, Doerr O, Weipert K, Rixe J, Liebetrau C, Elsaesser A, Achenbach S, Hamm C, Nef H (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Clinical Research in Cardiology Springer Verlag (Germany)

Publisher: Springer Verlag (Germany)

Book Volume: 103

Pages Range: 141-8

Journal Issue: 2

DOI: 10.1007/s00392-013-0630-x

Abstract

To evaluate safety and efficacy of the everolimus-eluting bioresorbable scaffold (BVS) in patients with ST-segment elevation myocardial infarction (STEMI).According to the current guidelines, drug-eluting stents are the treatment of choice in patients with STEMI. BVS represents a new technology capable to restore the native vessel vasomotion and potentially avoiding long-term limitations such as stent thrombosis.From October 2012 to May 2013, patients with evidence of STEMI eligible for BVS implantation were included in this study. Exclusion criteria were not defined.A total of 25 patients, respectively 31 lesions, were treated. Procedural success was achieved in 97 %. Two major adverse cardiac events occurred during hospitalization and follow-up: one patient with cardiogenic shock at the index procedure subsequently died. One patient suffered from instable angina with need for interventional revascularization of a previously untreated vessel. One target vessel failure as a consequence of an intra-procedural dissection was seen. However, no target lesion failure was noted. During 132.7 ± 68.7 days of follow-up none of the patients died.Our findings suggest that implantation of BVS in STEMI patients is feasible in this small cohort of highly selected patients. Further evaluation in randomized-controlled trials is needed.

Authors with CRIS profile

Stephan Achenbach Department of Medicine 2 – Cardiology and Angiology

Involved external institutions

Justus-Liebig-Universität Gießen DE Germany (DE) Kerckhoff-Klinik DE Germany (DE) Klinikum Oldenburg DE Germany (DE)

How to cite

APA:

Wiebe, J., Moellmann, H., Most, A., Doerr, O., Weipert, K., Rixe, J.,... Nef, H. (2014). Short-term outcome of patients with ST-segment elevation myocardial infarction (STEMI) treated with an everolimus-eluting bioresorbable vascular scaffold. Clinical Research in Cardiology, 103(2), 141-8. https://doi.org/10.1007/s00392-013-0630-x

MLA:

Wiebe, Jens, et al. "Short-term outcome of patients with ST-segment elevation myocardial infarction (STEMI) treated with an everolimus-eluting bioresorbable vascular scaffold." Clinical Research in Cardiology 103.2 (2014): 141-8.

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