New method for remote and repeatable monitoring of intraocular pressure variations
Margalit I, Beiderman Y, Skaat A, Rosenfeld E, Belkin M, Tornow RP, Mico V, Garcia J, Zalevsky Z (2014)
Publication Type: Journal article
Publication year: 2014
Journal
Publisher: Society of Photo-optical Instrumentation Engineers (SPIE)
Book Volume: 19
Pages Range: 027002
Journal Issue: 2
DOI: 10.1117/1.JBO.19.2.027002
Abstract
We present initial steps toward a new measurement device enabling high-precision, noncontact remote and repeatable monitoring of intraocular pressure (IOP)-based on an innovative measurement principle. Using only a camera and a laser source, the device measures IOP by tracking the secondary speckle pattern trajectories produced by the reflection of an illuminating laser beam from the iris or the sclera. The device was tested on rabbit eyes using two different methods to modify IOP: via an infusion bag and via mechanical pressure. In both cases, the eyes were stimulated with increasing and decreasing ramps of the IOP. As IOP variations changed the speckle distributions reflected back from the eye, data were recorded under various optical configurations to define and optimize the best experimental configuration for the IOP extraction. The association between the data provided by our proposed device and that resulting from controlled modification of the IOP was assessed, revealing high correlation (R2=0.98) and sensitivity and providing a high-precision measurement (5% estimated error) for the best experimental configuration. Future steps will be directed toward applying the proposed measurement principle in clinical trials for monitoring IOP with human subjects.
Involved external institutions
Bar-Ilan University
Israel (IL)
Tel Aviv University
Israel (IL)
University of València / Universitat de València
Spain (ES)
Israel (IL)
Tel Aviv University
Israel (IL)
University of València / Universitat de València
Spain (ES)
How to cite
APA:
Margalit, I., Beiderman, Y., Skaat, A., Rosenfeld, E., Belkin, M., Tornow, R.-P.,... Zalevsky, Z. (2014). New method for remote and repeatable monitoring of intraocular pressure variations. Journal of Biomedical Optics, 19(2), 027002. https://doi.org/10.1117/1.JBO.19.2.027002
MLA:
Margalit, Israel, et al. "New method for remote and repeatable monitoring of intraocular pressure variations." Journal of Biomedical Optics 19.2 (2014): 027002.
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