Agaimy A, Hartmann A (2016)
Publication Type: Journal article
Publication year: 2016
Book Volume: 37
Pages Range: 134-43
Journal Issue: 2
DOI: 10.1007/s00292-016-0153-0
Renal cell carcinomas are associated with hereditary tumor syndromes in approximately 5 % of cases. In patients with a hereditary predisposition, tumors show an earlier age of onset, often with a multicentric and bilateral manifestation. While some patients with renal cell carcinoma can be classified into well-characterized kidney cancer syndromes others have a genetic background which is still poorly understood. Most of the specific tumor syndromes are associated with a histopathologically distinct renal cell tumor phenotype. The recognition of patients with hereditary renal cell carcinoma and the identification of individual family members with a higher risk of development of renal tumors is important for early tumor detection and treatment. This manuscript reviews the clinical pathological and molecular findings of hereditary renal cell carcinoma syndromes.
APA:
Agaimy, A., & Hartmann, A. (2016). Hereditary renal tumors: More common than expected? Pathologe, 37(2), 134-43. https://doi.org/10.1007/s00292-016-0153-0
MLA:
Agaimy, Abbas, and Arndt Hartmann. "Hereditary renal tumors: More common than expected?" Pathologe 37.2 (2016): 134-43.
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