Treatment escalation in patients not responding to pharmacotherapy, psychotherapy, and electro-convulsive therapy: experiences from a novel regimen using intravenous S-ketamine as add-on therapy in treatment-resistant depression

Kallmünzer B, Volbers B, Karthaus A, Tektas OY, Kornhuber J, Mueller HH (2016)


Publication Type: Journal article

Publication year: 2016

Journal

Book Volume: 123

Pages Range: 549-52

Journal Issue: 5

DOI: 10.1007/s00702-015-1500-7

Abstract

A lack of response despite maximum therapy is common in patients fulfilling criteria of treatment-resistant depression. Therefore, innovative strategies for treatment escalation are warranted. Here, we report the clinical experiences associated with a novel therapeutic regimen combining electroconvulsive therapy and repeated intravenous S-ketamine treatment in three patients. The combined therapy was feasible and had no serious side effects. All patients responded to the new treatment option. The augmentative effect of sub-anesthetic S-ketamine on ECT is discussed.

Authors with CRIS profile

How to cite

APA:

Kallmünzer, B., Volbers, B., Karthaus, A., Tektas, O.Y., Kornhuber, J., & Mueller, H.H. (2016). Treatment escalation in patients not responding to pharmacotherapy, psychotherapy, and electro-convulsive therapy: experiences from a novel regimen using intravenous S-ketamine as add-on therapy in treatment-resistant depression. Journal of Neural Transmission, 123(5), 549-52. https://doi.org/10.1007/s00702-015-1500-7

MLA:

Kallmünzer, Bernd, et al. "Treatment escalation in patients not responding to pharmacotherapy, psychotherapy, and electro-convulsive therapy: experiences from a novel regimen using intravenous S-ketamine as add-on therapy in treatment-resistant depression." Journal of Neural Transmission 123.5 (2016): 549-52.

BibTeX: Download