Animal models of autoimmune liver diseases

Biburger M, Tiegs G (2007)


Publication Status: Published

Publication Type: Authored book, other

Publication year: 2007

Publisher: Humana Press

Pages Range: 293-306

ISBN: 9781588298188

DOI: 10.1007/978-1-59745-518-3_24

Abstract

The term autoimmune liver diseases in its common use comprises three types of disorders, namely, autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC), as well as their overlap syndromes. Previous reports (1,2) indicated an incidence (identified patients) of 1 to 2:10.000 for AIH, 1:10.000 for PBC, and 0.5:10.000 for PSC. However, there is a pronounced probability for significantly higher case numbers of unidentified autoimmune liver diseases owing to low severity of symptoms in the early stages, especially for PBC and PSC and also most of AIH cases. There is a predisposition of women to the development of AIH (3-4:1 female/ male patients) and PBC (9:1), whereas PSC predominantly affects men (1:2). © 2007 Humana Press Inc.

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How to cite

APA:

Biburger, M., & Tiegs, G. (2007). Animal models of autoimmune liver diseases. Humana Press.

MLA:

Biburger, Markus, and Gisa Tiegs. Animal models of autoimmune liver diseases. Humana Press, 2007.

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