Detection of monoamine oxidase a in brain of living rats with [(18) F]fluoroethyl-harmol PET

Cumming P, Skaper D, Kuwert T, Maschauer S, Prante O (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Synapse Wiley-Blackwell

Publisher: Wiley-Blackwell

Book Volume: 69

Pages Range: 57-9

Journal Issue: 1

DOI: 10.1002/syn.21785

Abstract

The efficient radiosynthesis for the MAO-A ligand [(18) F]fluoroethyl-harmol is reported. Initial PET examinations reveal the ligand to be retained throughout rat brain during 90 min, whereas pretreatment with pargyline results in substantially increased washout, from which binding potentials in the range of 1.4-2.1 can be calculated.

Authors with CRIS profile

Torsten Kuwert Lehrstuhl für Klinische Nuklearmedizin Simone Maschauer Professur für Molekulare Bildgebung und Radiochemie Olaf Prante Professur für Molekulare Bildgebung und Radiochemie

How to cite

APA:

Cumming, P., Skaper, D., Kuwert, T., Maschauer, S., & Prante, O. (2015). Detection of monoamine oxidase a in brain of living rats with [(18) F]fluoroethyl-harmol PET. Synapse, 69(1), 57-9. https://doi.org/10.1002/syn.21785

MLA:

Cumming, Paul, et al. "Detection of monoamine oxidase a in brain of living rats with [(18) F]fluoroethyl-harmol PET." Synapse 69.1 (2015): 57-9.

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