S3 guidelines on diagnostics and treatment of cervical cancer: Demands on pathology
Horn LC, Beckmann M, Follmann M, Koch M, Mallmann P, Marnitz S, Schmidt D (2015)
Publication Type: Journal article
Publication year: 2015
Journal
Book Volume: 36
Pages Range: 585-93
Journal Issue: 6
DOI: 10.1007/s00292-015-0114-z
Abstract
Between 2011 and the end of 2014 the former consensus S2k guidelines for the diagnostics and treatment of cervical cancer were updated and upgraded to S3 level, methodologically based on the regulations of the German Cancer Society (DKG). The present article summarizes the relevant aspects for the sectioning, histopathological workup, diagnostics and reporting for the pathology of invasive cancer of the uterine cervix. The recommendations are based on the most recent World Health Organization (WHO) and TNM classification systems and consider the needs of the clinician for appropriate surgical and radiotherapeutic treatment of patients. Detailed processing rules of colposcopy-guided diagnostic biopsies, conization and trachelectomy as well as for radical hysterectomy specimens and lymph node resection (including sentinel lymph node resection) are given. In the guidelines deep stromal invasion in macroinvasive cervical cancer is defined for the first time as tumor infiltration of > 66% of the cervical stromal wall. Furthermore, morphological prognostic factors for microinvasive and macroinvasive cervical cancer are summarized.
Authors with CRIS profile
Involved external institutions
Synlab MVZ Mannheim
Germany (DE)
Charité - Universitätsmedizin Berlin
Germany (DE)
Universität zu Köln
Germany (DE)
Deutsche Krebsgesellschaft (DKG)
Germany (DE)
Universitätsklinikum Leipzig
Germany (DE)
Germany (DE)
Charité - Universitätsmedizin Berlin
Germany (DE)
Universität zu Köln
Germany (DE)
Deutsche Krebsgesellschaft (DKG)
Germany (DE)
Universitätsklinikum Leipzig
Germany (DE)
How to cite
APA:
Horn, L.-C., Beckmann, M., Follmann, M., Koch, M., Mallmann, P., Marnitz, S., & Schmidt, D. (2015). S3 guidelines on diagnostics and treatment of cervical cancer: Demands on pathology. Pathologe, 36(6), 585-93. https://doi.org/10.1007/s00292-015-0114-z
MLA:
Horn, L. -C., et al. "S3 guidelines on diagnostics and treatment of cervical cancer: Demands on pathology." Pathologe 36.6 (2015): 585-93.
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