Champlin D, Frasch M, Saumweber H, Lis J (1991)
Publication Status: Published
Publication Type: Journal article, Original article
Publication year: 1991
Publisher: COLD SPRING HARBOR LAB PRESS
Book Volume: 5
Pages Range: 1611-1621
Journal Issue: 9
We have used indirect immunofluorescence of polytene chromosomes to examine the chromatin distribution of a 52-kD Drosophila protein designated B52. B52 is localized to transcriptionally active loci and, at the highly decondensed heat shock loci, can be seen to bracket the RNA polymerase II fluorescence signals symmetrically. We have also examined the distribution of B52 on nonpolytene chromosomes in Drosophila cell cultures with an in vivo UV cross-linking method and find that, here too, B52 is associated with boundaries of transcriptionally active chromatin. The predicted primary amino acid sequence of B52 reveals two regions with similarities to a number of other proteins known to interact with nucleic acids.
APA:
Champlin, D., Frasch, M., Saumweber, H., & Lis, J. (1991). CHARACTERIZATION OF A DROSOPHILA PROTEIN ASSOCIATED WITH BOUNDARIES OF TRANSCRIPTIONALLY ACTIVE CHROMATIN. Genes & Development, 5(9), 1611-1621.
MLA:
Champlin, DT, et al. "CHARACTERIZATION OF A DROSOPHILA PROTEIN ASSOCIATED WITH BOUNDARIES OF TRANSCRIPTIONALLY ACTIVE CHROMATIN." Genes & Development 5.9 (1991): 1611-1621.
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