Mesenchymal tumors of the mediastinum

Rieker RJ, Marx A, Agaimy A, Stroebel P (2016)

Publication Type: Journal article

Publication year: 2016

Journal

Pathologe Springer Verlag (Germany)

Book Volume: 37

Pages Range: 449-56

Journal Issue: 5

DOI: 10.1007/s00292-016-0190-8

Abstract

Mesenchymal neoplasms of the thymus and mediastinum account for only 2 % of neoplasms of the mediastinum and are therefore very rare. With very few exceptions the histology, immunohistochemistry and (based on current knowledge) molecular biology of mediastinal soft tissue tumors are not different from their counterparts in other organs. Characteristic features are more concerned with clinical epidemiological and therapeutic aspects as well as the multitude of possible differential diagnoses. With the exception of organ-specific tumors, such as gastrointestinal stromal tumors (GIST), virtually all entities encountered in peripheral soft tissues can also arise in the mediastinum. Primary mediastinal soft tissue sarcomas (STS) must be distinguished from secondary radiation-induced STS after irradiation, e. g. for breast cancer and Hodgkin's lymphoma and from STS arising as somatic type malignancies in mediastinal germ cell tumors.

Authors with CRIS profile

Abbas Agaimy Lehrstuhl für Allgemeine Pathologie und Pathologische Anatomie

Involved external institutions

Ruprecht-Karls-Universität Heidelberg DE Germany (DE) Universitätsklinikum Göttingen DE Germany (DE)

How to cite

APA:

Rieker, R.J., Marx, A., Agaimy, A., & Stroebel, P. (2016). Mesenchymal tumors of the mediastinum. Pathologe, 37(5), 449-56. https://doi.org/10.1007/s00292-016-0190-8

MLA:

Rieker, R. J., et al. "Mesenchymal tumors of the mediastinum." Pathologe 37.5 (2016): 449-56.

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