Therapeutic opportunities for targeting cold pain pathways
Yin K, Zimmermann K, Vetter I, Lewis RJ (2015)
Publication Type: Journal article
Publication year: 2015
Journal
Book Volume: 93
Pages Range: 125-40
Journal Issue: 2
DOI: 10.1016/j.bcp.2014.09.024
Abstract
Cold pain is a frequent symptom in neuropathic pain. Compared to other pain modalities, such as heat pain, the mechanisms behind physiological and pathological cold pain remain elusive. Moreover, it is becoming increasingly evident that cold pain pharmacology differs between various neuropathic pain conditions, making mechanism-directed treatment based on an understanding of the underlying pathophysiological mechanisms imperative to achieving clinical success. Here we review the processes of physiological and abnormal cold sensing, the pharmacology of cold nociception, cold hyperalgesia and cold allodynia, and provide an overview of cold pain syndromes and their current and potential treatments.
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APA:
Yin, K., Zimmermann, K., Vetter, I., & Lewis, R.J. (2015). Therapeutic opportunities for targeting cold pain pathways. Biochemical Pharmacology, 93(2), 125-40. https://doi.org/10.1016/j.bcp.2014.09.024
MLA:
Yin, Kathleen, et al. "Therapeutic opportunities for targeting cold pain pathways." Biochemical Pharmacology 93.2 (2015): 125-40.
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