Quantification of an external motion surrogate for quality assurance in lung cancer radiation therapy

Wölfelschneider J, Brandt T, Lettmaier S, Fietkau R, Bert C (2014)


Publication Type: Journal article

Publication year: 2014

Journal

Publisher: Hindawi Publishing Corporation

Book Volume: 2014

Pages Range: 595430

DOI: 10.1155/2014/595430

Abstract

The purpose of this work was to validate the stability of the end exhale position in deep expiration breath hold (DEBH) technique for quality assurance in stereotactic lung tumor radiation therapy. Furthermore, a motion analysis was performed for 20 patients to evaluate breathing periods and baseline drifts based on an external surrogate. This trajectory was detected using stereo infrared (IR) cameras and reflective body markers. The respiratory waveform showed large interpatient differences in the end exhale position during irradiation up to 18.8 mm compared to the global minimum. This position depends significantly on the tumor volume. Also the baseline drifts, which occur mostly in posterior direction, are affected by the tumor size. Breathing periods, which depend mostly on the patient age, were in a range between 2.4 s and 7.0 s. Fifteen out of 20 patients, who showed a reproducible end exhale position with a deviation of less than 5 mm, might benefit from DEBH due to smaller planning target volumes (PTV) compared to free breathing irradiation and hence sparing of healthy tissue. Patients with larger uncertainties should be treated with more complex motion compensation techniques.

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How to cite

APA:

Wölfelschneider, J., Brandt, T., Lettmaier, S., Fietkau, R., & Bert, C. (2014). Quantification of an external motion surrogate for quality assurance in lung cancer radiation therapy. BioMed Research International, 2014, 595430. https://doi.org/10.1155/2014/595430

MLA:

Wölfelschneider, Jens, et al. "Quantification of an external motion surrogate for quality assurance in lung cancer radiation therapy." BioMed Research International 2014 (2014): 595430.

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