Bärenwaldt A, Biburger M, Nimmerjahn F (2010)
Publication Status: Published
Publication Type: Journal article, Review article
Publication year: 2010
Publisher: Expert Reviews (formerly Future Drugs)
Book Volume: 6
Pages Range: 425-434
Journal Issue: 3
DOI: 10.1586/eci.10.9
Intravenous immunoglobulin (IVIg) has been used for nearly three decades as an efficient anti-inflammatory therapeutic regimen in a growing number of autoimmune diseases. Despite this their success in clinical application, the mechanism of action of IVIg therapy remains elusive. During the last few years, several mechanisms dependent on either the IgG variable or constant fragment have been proposed to explain the potent immunomodulatory activity of IVIg. This review will discuss which molecular and cellular pathways might be involved in the anti-inflammatory activity of IVIg and for which types of autoimmune diseases they might be relevant. © 2010 Expert Reviews Ltd.
APA:
Bärenwaldt, A., Biburger, M., & Nimmerjahn, F. (2010). Mechanisms of action of intravenous immunoglobulins. Expert Review of Clinical Immunology, 6(3), 425-434. https://doi.org/10.1586/eci.10.9
MLA:
Bärenwaldt, Anne, Markus Biburger, and Falk Nimmerjahn. "Mechanisms of action of intravenous immunoglobulins." Expert Review of Clinical Immunology 6.3 (2010): 425-434.
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