Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms
Wagner F, Kuder TA, Mlynarska A, Maier F, Faust J, Demberg K, Lindemann L, Rivkin B, Nagel AM, Ladd ME, Maier-Hein K, Bickelhaupt S, Bach M, Laun FB (2017)
Publication Type: Journal article
Publication year: 2017
Journal
Book Volume: 12
Pages Range: e0179276
Journal Issue: 6
DOI: 10.1371/journal.pone.0179276
Abstract
To use the "apparent diffusion coefficient" (Dapp) as a quantitative imaging parameter, well-suited test fluids are essential. In this study, the previously proposed aqueous solutions of polyvinylpyrrolidone (PVP) were examined and temperature calibrations were obtained. For example, at a temperature of 20°C, Dapp ranged from 1.594 (95% CI: 1.593, 1.595) ?m2/ms to 0.3326 (95% CI: 0. 3304, 0.3348) ?m2/ms for PVP-concentrations ranging from 10% (w/w) to 50% (w/w) using K30 polymer lengths. The temperature dependence of Dapp was found to be so strong that a negligence seems not advisable. The temperature dependence is descriptively modelled by an exponential function exp(c2 (T - 20°C)) and the determined c2 values are reported, which can be used for temperature calibration. For example, we find the value 0.02952 K-1 for 30% (w/w) PVP-concentration and K30 polymer length. In general, aqueous PVP solutions were found to be suitable to produce easily applicable and reliable Dapp-phantoms.
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Germany (DE)How to cite
APA:
Wagner, F., Kuder, T.A., Mlynarska, A., Maier, F., Faust, J., Demberg, K.,... Laun, F.B. (2017). Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms. PLoS ONE, 12(6), e0179276. https://doi.org/10.1371/journal.pone.0179276
MLA:
Wagner, Friedrich, et al. "Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms." PLoS ONE 12.6 (2017): e0179276.
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