Downregulation of Checkpoint Protein Kinase 2 in the Urothelium of Healthy Male Tobacco Smokers

Breyer J, Denzinger S, Hartmann A, Otto W (2016)

Publication Type: Journal article

Publication year: 2016

Journal

Urologia Internationalis Karger

Book Volume: 97

Pages Range: 480-481

Journal Issue: 4

DOI: 10.1159/000446827

Abstract

With this letter to the editor we present for the first time a study on CHEK2 expression in normal urothelium of healthy male smokers, former smokers and non-smokers. We could show a statistically significant downregulation of this DNA repair gene in current smokers compared to non-smokers, suggesting that smoking downregulates CHEK2 in normal urothelium, probably associated with an early step in carcinogenesis of urothelial bladder carcinoma.

Authors with CRIS profile

Arndt Hartmann Lehrstuhl für Allgemeine Pathologie und Pathologische Anatomie

Involved external institutions

Universität Regensburg DE Germany (DE)

How to cite

APA:

Breyer, J., Denzinger, S., Hartmann, A., & Otto, W. (2016). Downregulation of Checkpoint Protein Kinase 2 in the Urothelium of Healthy Male Tobacco Smokers. Urologia Internationalis, 97(4), 480-481. https://doi.org/10.1159/000446827

MLA:

Breyer, Johannes, et al. "Downregulation of Checkpoint Protein Kinase 2 in the Urothelium of Healthy Male Tobacco Smokers." Urologia Internationalis 97.4 (2016): 480-481.

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