FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.11.2025
End date : 30.04.2026
We are investigating the phenotypic diversity of patient-specific PAX2 variants in kidney diseases such as CAKUT and SRNS. For this purpose, we differentiate patient-derived iPSCs into various kidney cells in 2D and 3D organoids, compared with healthy control cells and gene-corrected variants. This approach helps to understand genetic and environmental factors in kidney diseases and to develop personalized therapies