IZKF-N12 Autoimmuntherap.uT-Zell(341/M3): T cell plasticity and functionality under conventional autoimmune disease therapies

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.04.2025

End date : 31.03.2027


Project details

Scientific Abstract

The proposed project will investigate the effect of common therapies such as hydroxychloroquine, tocilizumab, mycophenolate mofetil or rituximab in systemic lupus and systemic sclerosis patients. Closing a major gap in our knowledge of how distinct therapies influence T cell differentiation, metabolic reprogramming, subsets distribution and effector functions; this study will guide the improvement of disease management to favour immune competence.

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Research Areas