P149: Podocyte specific targeting with functionalized drug loaded nanoparticles for precision medicine
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.01.2025
End date : 31.12.2025
Project details
Scientific Abstract
Lipid nanocapsules, functionalized with RGD sequence to target ?V?3 integrin receptor on podocytes and loaded with therapeutic substances will be investigated as a podocyte specific therapeutic strategy. Uptake and therapeutic potential of loaded nanoparticles to rescue proteinuric phenotypes will be investigated in different zebrafish glomerular disease models. These experiments enable in vivo analysis of nanocarriers as potential cell type specific drug delivery systems.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 4 – Nephrology and Hypertension
Medizinische Fakultät
Professur für seltene Nierenerkrankungen
