Kinase signaling in the immune responses of small-cell lung cancer

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.04.2024

Project details

Scientific Abstract

Our preliminary results suggest that kinases are deregulated in SCLC during metastasis and resistance to immune checkpoint blockade and helps the tumor to escape the immune system. We plan to investigate kinase inhibitors for their immunoregulatory properties and elucidate the molecular mechanisms downstream of responsible kinases and identify patients who may benefit from targeted therapy.

Involved:

Lydia Meder Project Leader Ilayda Kocak Project Member Daniel Fröba Project Member

Contributing FAU Organisations:

Interdisziplinäres Zentrum für Klinische Forschung IZKF-Förderlinien Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung Einrichtungen, die nicht zum Universitätsklinikum Erlangen gehören Klinisch-Molekularbiologisches Forschungszentrum Medizinische Fakultät Professur für Zellplastizität am Tumor-Host-Interface