Cancer cell colonization of the lung epithelium

Internally funded project


Start date : 01.09.2023

Project details

Scientific Abstract

The lungs are frequently affected by metastases of various solid cancers including breast-, colon- and pancreatic cancer. When cancer cells disseminate from their primary site and reach a foreign tissue microenvironment, cancer cell need to adapt, survive and subsequently proliferate to form metastases. Unravelling the mechanisms driving this post-extravasation behaviour is an experimentally challenging problem in cancer research which we aim to address.

Involved:

Lydia Meder Project Leader Anna Dmitrieva Project Member Elisabetta D'Avanzo Project Member

Contributing FAU Organisations:

Lehrstuhl für Experimentelle Medizin mit dem Schwerpunkt Molekulare Pathogeneseforschung Einrichtungen, die nicht zum Universitätsklinikum Erlangen gehören Klinisch-Molekularbiologisches Forschungszentrum Medizinische Fakultät Sonderforschungsbereich/Transregio 305/1: Über die Analyse der metastatischen Koloniebildung zu neuen systemischen Krebstherapien Professur für Zellplastizität am Tumor-Host-Interface