P139: Modulation of Pain Perception by 3-Indolepropionic Acid in Arthritis: Implications for the Clinical Course
FAU own research funding: EFI / IZKF / EAM ...
Start date : 16.06.2024
End date : 15.05.2025
Project details
Scientific Abstract
Our preliminary study demonstrated protective effects of 3-indolepropionic acid (IPA) on the severity of CIA arthritis in mice. Our project will now I) provide insight into general IPA effects on overall brain function at rest and II) use (thermal) fMRI to evaluate central nociception as a functional readout parameter for RA severity. III) We will assess whether long-term IPA treatment up to day 35 may have additional benefits on disease progression.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Lehrstuhl für Pharmakologie und Toxikologie
Medizinische Fakultät
