P142: Investigation of stromal IL36R signaling during intestinal inflammation and fibrosis

FAU own research funding: EFI / IZKF / EAM ...


Start date : 16.11.2023

End date : 15.11.2024


Project details

Scientific Abstract

Intestinal fibrosis is a common complication in IBD with an unmet need to develop therapy options. Recent studies turned fibroblasts into the spotlight of IBD research as they are associated with fibrosis, control of inflammation and personalized therapy. Published own work showed a major role of IL36R signaling during the perpetuation of intestinal inflammation/fibrosis. This project aims to understand the role of stromal IL36R signaling for the resolution of intestinal inflammation/fibrosis.

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