J109: EV profiling: a potential window into the pathogenesis of Parkinsons disease

FAU own research funding: EFI / IZKF / EAM ...

Start date : 01.01.2024

End date : 30.06.2026

Overview

Project details

Scientific Abstract

The aim of this project is to facilitate the understanding of the role of extracellular vesicles (EVs) in the development and progression of Parkinsons disease (PD). EVs extracted from blood of PD patients and controls will be fractionated according to cellular origin and cargo profiling will be performed focusing on pathogenic forms of aSyn and regulatory RNAs. The results will offer deeper insights in PD-related signatures, and permit exploring the origin and transfer of pathogenic molecules.

Involved:

Fanni Annamaria Boros Project Leader Philipp Arnold Project Member Gregor Fuhrmann Project Member

Contributing FAU Organisations:

Interdisziplinäres Zentrum für Klinische Forschung (IZKF) Department of Molecular Neurology Lehrstuhl für Pharmazeutische Biologie Lehrstuhl für Funktionelle und Klinische Anatomie Medizinische Fakultät

Research Areas