P043: The effect of anti-tumor therapy on the autotaxinLPA axis in breast cancer
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.07.2019
End date : 24.08.2020
Extension date: 24.02.2021
Project details
Scientific Abstract
Breast cancer is the most common cancer in women worldwide. It is hypothesized that in a vicious cycle autotaxin (ATX) secreted by fat tissue influences breast cancer cells in behavior and leads to secretion of inflammatory cytokines which in turn stimulate ATX secretion of fat tissue. Radiotherapy could lead to an amplification of this effect. It is the aim of this study to evaluate the significance of the ATX/LPA-axis and the effect of radiotherapy in different breast cancer subtypes.
Involved:
Contributing FAU Organisations:
Department of Plastic and Hand Surgery
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Medizinische Fakultät
