IZKF-J77 (M3): Phenotypic and Transcriptional Characterization of Auto-reactive B cells In Rheumatoid Arthritis
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.11.2019
End date : 30.04.2022
Project details
Scientific Abstract
Rheumatoid arthritis is a common autoimmune disease. Anti-citrullinated-protein antibodies (ACPAs) have been identified as key players in RA . But a better understanding of the ACPA-producing B cells and of the transcriptional events in ACPA-specific B cells during the onset of RA is essential. Therefore, we plan to perform an in depth molecular characterization of the dynamic changes occurring inside the ACPA-specific B cell compartment during different phases of RA pathogenesis.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
Medizinische Fakultät
