Prof. Dr. Friederike Zunke

Juniorprofessur für Translationale Neurowissenschaften Professur für Translationale Neurowissenschaften

Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide (2018) Zunke F, Moise AC, Belur NR, Gelyana E, Stojkovska I, Dzaferbegovic H, Toker NJ, et al. Journal article The shedding protease ADAM17: Physiology and pathophysiology (2017) Zunke F, Rose-John S Journal article, Review article Activation of β-glucocerebrosidase reduces pathological α-synuclein and restores lysosomal function in Parkinson’s patient midbrain neurons (2016) Mazzulli JR, Zunke F, Tsunemi T, Toker NJ, Jeon S, Burbulla LF, Patnaik S, et al. Journal article Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2 (2016) Zunke F, Andresen L, Wesseler S, Groth J, Arnold P, Rothaug M, Mazzulli JR, et al. Journal article α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models (2016) Mazzulli JR, Zunke F, Isacson O, Studer L, Krainc D Journal article Mannose 6-phosphate-independent Lysosomal Sorting of LIMP-2 (2015) Blanz J, Zunke F, Markmann S, Damme M, Braulke T, Saftig P, Schwake M Journal article Calcium negatively regulates meprin b activity and attenuates substrate cleavage (2015) Arnold P, Schmidt F, Prox J, Zunke F, Pietrzik C, Lucius R, Becker-Pauly C Journal article Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease (2015) Peters J, Rittger A, Weisner R, Knabbe J, Zunke F, Rothaug M, Damme M, et al. Journal article LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease (2015) Rothaug M, Stroobants S, Schweizer M, Peters J, Zunke F, Allerding M, D'Hooge R, et al. Journal article LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance (2014) Rothaug M, Zunke F, Mazzulli JR, Schweizer M, Altmeppen H, Luellmann-Rauch R, Kallemeijn WW, et al. Journal article