PD Dr. Heiko Bruns

Department of Medicine 5 – Haematology and Oncology

Deciphering the role of HLA-DO in immune responses after allogeneic stem cell transplantation (2021) Zeun J, Flamann C, Neubeck S, Bausenwein J, Seyler L, Vogler T, Brey S, et al. Conference contribution Severity of COVID-19 disease is related to hyperactivation and altered migratory capacity of T cells (2021) Spörl S, Kremer AL, Aigner M, Eisenhauer N, Koch P, Meretuk L, Loeffler P, et al. Conference contribution β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression (2021) Hofbauer D, Mougiakakos D, Broggini L, Zaiss M, Büttner-Herold M, Bach C, Spriewald B, et al. Journal article Select hyperactivating NLRP3 ligands enhance the TH1-and TH17-inducing potential of human type 2 conventional dendritic cells (2021) Hatscher L, Lehmann C, Purbojo A, Onderka C, Liang C, Hartmann A, Cesnjevar R, et al. Journal article, Original article Upregulation of CCR4 in activated CD8(+) T cells indicates enhanced lung homing in patients with severe acute SARS-CoV-2 infection (2021) Spoerl S, Kremer A, Aigner M, Eisenhauer N, Koch P, Meretuk L, Loeffler P, et al. Journal article The IKZF1–IRF4/IRF5 axis controls polarization of myeloma-associated macrophages (2021) Mougiakakos D, Bach C, Böttcher M, Beier F, Röhner L, Stoll A, Rehli M, et al. Journal article CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity (2021) Stoll A, Bruns H, Fuchs M, Nimmerjahn F, Kunz M, Peipp M, Mackensen A, et al. Journal article Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis (2021) Böttcher M, Bruns H, Völkl S, Lu J, Chartomatsidou E, Papakonstantinou N, Mentz K, et al. Journal article The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts (2021) Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp S, Walker KI, et al. Journal article, Original article Selective elimination of immunosuppressive T cells in patients with multiple myeloma (2021) Awwad MHS, Mahmoud A, Bruns H, Echchannaoui H, Kriegsmann K, Lutz R, Raab MS, et al. Journal article