PD Dr. Manuela Krumbholz

Department of Paediatrics and Adolescent Medicine

Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients (2024) Hovorkova L, Winkowska L, Skorepova J, Krumbholz M, Benesova A, Polivkova V, Alten J, et al. Journal article Somatic variant profiling in chronic phase pediatric chronic myeloid leukemia. (2024) Behrens YL, Gaschler L, Nienhold R, Reinkens T, Schirmer E, Knöβ S, Strasser R, et al. Journal article Synergistic lethality in chronic myeloid leukemia – targeting oxidative phosphorylation and unfolded protein response effectively complements tyrosine kinase inhibitor treatment (2023) Häselbarth L, Gamali S, Saul D, Krumbholz M, Böttcher-Loschinski R, Böttcher M, Zou D, et al. Journal article Continuous therapy response references for BCR::ABL1 monitoring in pediatric chronic myeloid leukemia (2023) Volz C, Zerjatke T, Gottschalk A, Semper S, Suttorp M, Glauche I, Krumbholz M, Metzler M Journal article Temporal evolution and differential patterns of cellular reconstitution after therapy for childhood cancers (2023) Hofmann G, Zierk J, Sobik B, Wotschofsky Z, Sembill S, Krumbholz M, Metzler M, Karow A Journal article Management of children and adolescents with chronic myeloid leukemia in blast phase: International pediatric CML expert panel recommendations (2023) Sembill S, Ampatzidou M, Chaudhury S, Dworzak M, Kalwak K, Karow A, Kiani A, et al. Journal article, Review article Effects of the STAMP-inhibitor asciminib on T cell activation and metabolic fitness compared to tyrosine kinase inhibition by imatinib, dasatinib, and nilotinib (2023) Häselbarth L, Karow A, Mentz K, Böttcher M, Roche-Lancaster O, Krumbholz M, Jitschin R, et al. Journal article Patient-reported health-related quality of life (HRQOL) following allogeneic stem cell transplantation (SCT) performed early after diagnosis of pediatric chronic myeloid leukemia (CML) (2022) Schleicher O, Horndasch A, Krumbholz M, Sembill S, Karow A, Bremensdorfer C, Grabow D, et al. Conference contribution Patient-reported long-term outcome following allogeneic hematopoietic stem cell transplantation in pediatric chronic myeloid leukemia (2022) Schleicher O, Horndasch A, Krumbholz M, Sembill S, Bremensdorfer C, Grabow D, Erdmann F, et al. Journal article Targeting metabolism effectively complements tyrosine kinase inhibitor treatment of chronic myeloid leukemia (2022) Häselbarth L, Saul D, Krumbholz M, Mougiakaos D, Metzler M, Karow A Conference contribution