Prof. Dr. Thomas Gramberg

Medizinische Fakultät Juniorprofessur für Antivirale Native Immunität Institute of Clinical and Molecular Virology

Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner (2023) Schumann T, Ramon SC, Schubert N, Mayo MA, Hega M, Maser KI, Ada SR, et al. Journal article Nsp16 shields SARS–CoV-2 from efficient MDA5 sensing and IFIT1-mediated restriction (2022) Ruß A, Wittmann S, Tsukamoto Y, Herrmann A, Deutschmann J, Lagisquet J, Enßer A, et al. Journal article Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit (2022) Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, et al. Conference contribution Transmembrane serine protease 2 (TMPRSS2) is involved in proteolytic activation of the epithelial sodium channel (ENaC) in mouse cortical collecting duct (mCCDcl1) cells (2022) Sure F, Afonso S, Bertog M, Rinke R, Wittmann S, Gramberg T, Ilyaskin A, Korbmacher C Conference contribution Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases (2022) Bergant V, Yamada S, Grass V, Tsukamoto Y, Lavacca T, Krey K, Muhlhofer MT, et al. Journal article Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's gamma-subunit (2022) Sure F, Bertog M, Afonso S, Diakov A, Rinke R, Madej MG, Wittmann S, et al. Journal article SAMHD1 … and Viral Ways around It. (2021) Deutschmann J, Gramberg T Journal article, Review article Recognize Yourself-Innate Sensing of Non-LTR Retrotransposons (2021) Lagisquet J, Zuber K, Gramberg T Journal article, Review article Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells (2020) Bosso M, Prelli Bozzo C, Hotter D, Volcic M, Stürzel CM, Rammelt A, Ni Y, et al. Journal article Human TRIM5 alpha senses and restricts LINE-1 elements (2020) Volkmann B, Wittmann S, Lagisquet J, Deutschmann J, Eißmann K, Ross JJ, Biesinger B, Gramberg T Journal article