Prof. Dr. Lars Nitschke

Professur für Genetik

Siglec-G Regulates B1 Cell Survival and Selection (2010) Jellusova J, Dueber S, Gueckel E, Binder CJ, Weiss S, Voll R, Nitschke L Journal article CD22 x Siglec-G Double-Deficient Mice Have Massively Increased B1 Cell Numbers and Develop Systemic Autoimmunity (2010) Jellusova J, Wellmann U, Amann KU, Winkler T, Nitschke L Journal article Swiprosin-1/EFhd2 Controls B Cell Receptor Signaling through the Assembly of the B Cell Receptor, Syk, and Phospholipase C gamma 2 in Membrane Rafts (2010) Kroczek C, Lang C, Brachs S, Grohmann M, Duetting S, Schweizer A, Nitschke L, et al. Journal article CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions (2009) Nitschke L Journal article, Review article Regulation of Repertoire Development through Genetic Control of D(H) Reading Frame Preference (2008) Zemlin M, Schelonka RL, Ippolito GC, Zemlin C, Zhuang Y, Gartland GL, Nitschke L, et al. Journal article Novel mouse mutants with primary cellular immunodeficiencies generated by genome-wide mutagenesis (2008) Jakob T, Koellisch GV, Howaldt M, Bewersdorff M, Rathkolb B, Mueller ML, Sandholzer N, et al. Journal article Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population (2007) Hoffmann A, Kerr S, Jellusova J, Zhang J, Weisel F, Wellmann U, Winkler T, et al. Journal article B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity (2007) Pao LI, Lam KP, Henderson JM, Kutok JL, Alimzhanov M, Nitschke L, Thomas ML, et al. Journal article IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta (2007) Nitschke L Journal article Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production (2006) Ippolito GC, Schelonka RL, Zemlin M, Ivanov I, Kobayashi R, Zemlin C, Gartland GL, et al. Journal article