Dr. rer. nat. Martin Böttcher

Department of Medicine 5 – Haematology and Oncology

Bone marrow stroma cells promote a S100A8/A9high subset of chemoresistant AML blasts with distinct metabolic features in a Jak/STAT-dependent manner (2019) Böttcher M, Panagiotidis K, Mentz K, Bruns H, Mackensen A, Mougiakakos D, Völkl S Conference contribution Monitoring of the immunometabolic profile of reconstituting leukocytes upon autologous peripheral blood stem cell transplantation (2019) Richter S, Jacobs B, Böttcher M, Stoll A, Böttcher-Loschinski R, Mackensen A, Mougiakakos D Conference contribution Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity (2019) Lu J, Böttcher M, Walther T, Mougiakakos D, Zenz T, Huber W Journal article Inflammation-induced glycolytic switch controls suppressivity of mesenchymal stem cells via STAT1 glycosylation (2019) Jitschin R, Böttcher M, Saul D, Lukassen S, Bruns H, Loschinski R, Ekici AB, et al. Journal article A novel immunoregulatory function of beta-2-microglobulin as a promoter of myeloid derived suppressor cell induction (2019) Bruns H, Jitschin S, Gamali S, Saul D, Böttcher M, Mackensen A, Jitschin R, Mougiakakos D Journal article Stroma Cells Promote a S100A8/A9(high)-Subset of AML Blasts with Distinct Metabolic Features in a Jak/STAT3-Dependent Manner (2018) Böttcher M, Panagiotidis K, Mackensen A, Mougiakakos D Conference contribution D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization (2018) Böttcher M, Renner K, Berger R, Mentz K, Thomas S, Cardenas-Conejo ZE, Dettmer K, et al. Journal article Lenalidomide enhances MOR202-dependent macrophage-mediated effector functions via the vitamin D pathway (2018) Busch L, Mougiakakos D, Büttner-Herold M, Müller MJ, Volmer DA, Bach C, Fabri M, et al. Journal article IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner (2018) Loschinski R, Böttcher M, Stoll A, Bruns H, Mackensen A, Mougiakakos D Journal article Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss (2018) Lucas S, Omata Y, Hofmann J, Böttcher M, Iljazovic A, Sarter K, Albrecht O, et al. Journal article