Lead Discovery Center GmbH

Industry / private company


Location: Dortmund, Germany (DE) DE

ISNI: -

ROR: https://ror.org/02jy4mx12

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Types of publications

Journal article
Book chapter / Article in edited volumes
Authored book
Translation
Thesis
Edited Volume
Conference contribution
Other publication type
Unpublished / Preprint

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Abstract

Journal

Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency (2023) Schütz M, Wangen C, Sommerer M, Kögler M, Eickhoff J, Degenhart C, Klebl B, et al. Journal article Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target (2023) Tillmanns J, Häge S, Borst EM, Wardin J, Eickhoff J, Klebl B, Wagner S, et al. Journal article Combined Treatment with Host-Directed and Anticytomegaloviral Kinase Inhibitors: Mechanisms, Synergisms and Drug Resistance Barriers. (2023) Wild M, Karner D, Eickhoff J, Wagner S, Kicuntod J, Chang W, Barry P, et al. Journal article Combinatorial drug treatments reveal promising anticytomegaloviral profiles for clinically relevant pharmaceutical kinase inhibitors (PKIs) (2021) Wild M, Kicuntod J, Seyler L, Wangen C, Bertzbach LD, Conradie AM, Kaufer BB, et al. Journal article In vivo proof-of-concept for two experimental antiviral drugs, both directed to cellular targets, using a murine cytomegalovirus model (2019) Sonntag E, Hahn F, Bertzbach LD, Seyler L, Wangen C, Müller R, Tannig P, et al. Journal article New insights into the intracellular distribution pattern of cationic amphiphilic drugs (2017) Vater M, Möckl L, Gormanns V, Schultz Fademrecht C, Mallmann AM, Ziegart-Sadowska K, Zaba M, et al. Journal article The interaction between cyclin B1 and cytomegalovirus protein kinase pUL97 is determined by an active kinase domain (2015) Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, Sticht H, Marschall M Journal article, Original article A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations (2015) Hutterer C, Eickhoff J, Milbradt J, Korn K, Zeitträger I, Bahsi H, Wagner S, et al. Journal article