Netherlands Cancer Institute (NKI)

Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced NRAS- or BRAF-mutated melanoma (2019) Van Herpen CM, Agarwala SS, Hauschild A, Berking C, Thaddeus Beck J, Schadendorf D, Jansen R, et al. Journal article Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma (2019) Brummer C, Faerber S, Bruss C, Blank C, Lacroix R, Haferkamp S, Herr W, et al. Journal article Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers (2019) Siddiqui A, Gollavilli PN, Schwab A, Vazakidou ME, Ersan PG, Ramakrishnan M, Pluim D, et al. Journal article Estimation of the α/β ratio of non-small cell lung cancer treated with stereotactic body radiotherapy (2019) Klement RJ, Sonke JJ, Allgäuer M, Andratschke N, Appold S, Belderbos J, Belka C, et al. Journal article Resection of pancreatic cancer in Europe and USA: An international large-scale study highlighting large variations (2019) Huang L, Jansen L, Balavarca Y, Molina-Montes E, Babaei M, Van Der Geest L, Lemmens V, et al. Journal article CD4+ T cell help in cancer immunology and immunotherapy (2018) Borst J, Ahrends T, Babala N, Melief CJM, Kastenmueller W Journal article, Review article Targeting tumor-associated acidity in cancer immunotherapy (2018) Lacroix R, Rozeman EA, Kreutz M, Renner K, Blank CU Journal article, Review article Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study. (2018) van der Valk MJ, Hilling DE, Bastiaannet E, Meershoek-Klein Kranenbarg E, Beets GL, Figueiredo NL, Habr-Gama A, et al. Journal article Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium (2018) Rudolph A, Song M, Brook MN, Milne RL, Mavaddat N, Michailidou K, Bolla MK, et al. Journal article Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: MONALEESA-3 (2018) Slamon DJ, Neven P, Chia S, Fasching P, De Laurentiis M, Im SA, Petrakova K, et al. Journal article