Lehrstuhl für Biotechnik (Proteinstruktur und -design)

The Coxiella burnetii T4SS effector protein AnkG hijacks the 7SK small nuclear ribonucleoprotein complex for reprogramming host cell transcription (2022) Cordsmeier A, Rinkel S, Jeninga M, Schulze-Lührmann J, Oelke M, Schmid B, Hasler D, et al. Journal article A PROSS-designed extensively mutated estrogen receptor α variant displays enhanced thermal stability while retaining native allosteric regulation and structure (2021) Kriegel M, Wiederanders HJ, Alkhashrom S, Eichler J, Muller Y Journal article Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers (2021) Schweininger J, Scherer M, Rothemund F, Schilling EM, Worz S, Stamminger T, Muller Y Journal article Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors (2021) Alkhashrom S, Kicuntod J, Häge S, Schweininger J, Muller Y, Lischka P, Marschall M, Eichler J Journal article Crystal structures of adenylylated and unadenylylated PII protein GlnK from Corynebacterium glutamicum (2021) Grau F, Burkovski A, Muller Y Journal article Recombinant protein production and purification of SiiD, SiiE and SiiF - Components of the SPI4-encoded type I secretion system from Salmonella Typhimurium (2020) Klingl S, Kordes S, Schmid B, Gerlach R, Hensel M, Muller Y Journal article Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties (2020) Marschall M, Häge S, Conrad M, Alkhashrom S, Kicuntod J, Schweininger J, Kriegel M, et al. Journal article, Review article The CD83 Molecule – An Important Immune Checkpoint (2020) Grosche L, Knippertz I, König C, Royzman D, Wild A, Zinser E, Sticht H, et al. Journal article, Review article The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA-TetR regulator complex (2020) Grau F, Jaeger J, Groher F, Süss B, Muller Y Journal article High-resolution crystal structures of two prototypical β- And γ-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity (2020) Muller Y, Häge S, Alkhashrom S, Höllriegl T, Weigert S, Dolles S, Hof K, et al. Journal article