Lehrstuhl für Biochemie und Pathobiochemie

Heterozygous SOX9 mutations allowing for residual DNA-binding and transcriptional activation lead to the acampomelic variant of Campomelic Dysplasia. (2010) Wegner M Journal article, Original article Organogenesis relies on Sox4, Sox11, and Sox12 for survival of neural and mesenchymal progenitor cells. (2010) Sock E, Wegner M Journal article Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage. (2010) Wegner M Journal article, Original article The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development. (2010) Hartwig A, Wegner M, Sock E Journal article, Original article All purpose SOX: The many roles of Sox proteins in gene expression. (2010) Wegner M Journal article, Review article Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene. (2010) Sock E, Wegner M Journal article, Original article Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. (2010) Wegner M Journal article, Original article Replacement of mouse Sox10 by the Drosophila ortholog Sox100B provides evidence for co-option of SoxE proteins into vertebrate-specific gene-regulatory networks through altered expression. (2010) Sock E, Wegner M Journal article, Original article Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells. (2010) Reiprich S, Müller J, Wegner M Journal article, Original article Replacement of related POU transcription factors leads to severe defects in mouse forebrain development. (2009) Sock E, Reiprich S, Müller J, Stolt C, Wegner M Journal article, Original article