Professur für Genetik

The new semisynthetic cardenolide analog 3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) efficiently suppresses cell growth in human leukemia and urologic tumor cell lines (2015) Nolte E, Sobel A, Wach S, Hertlein H, Ebert N, Müller-Uri F, Slany R, et al. Journal article, Original article Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango. (2014) Hoyer S, Prommersberger S, Pfeiffer I, Schuler-Thurner B, Schuler G, Dörrie J, Schaft N Journal article Triggering of NF-κB in cytokine-matured human DCs generates superior DCs for T-cell priming in cancer immunotherapy. (2014) Pfeiffer I, Hoyer S, Gerer K, Voll RE, Knippertz I, Gueckel E, Schuler G, et al. Journal article The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module (2014) Engels N, Koenig LM, Schulze W, Radtke D, Vanshylla K, Lutz J, Winkler T, et al. Journal article CD22 and Siglec-G regulate inhibition of B-cell signaling by sialic acid ligand binding and control B-cell tolerance (2014) Nitschke L Journal article, Review article SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders (2014) Simonetti G, Bertilaccio MTS, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, et al. Journal article A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels (2014) Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, et al. Journal article Discovery of Multifold Modified Sialosides as Human CD22/Siglec-2 Ligands with Nanomolar Activity on B-Cells (2014) Prescher H, Schweizer A, Kuhfeldt E, Nitschke L, Brossmer R Journal article, Original article The role of CD22 and Siglec-G in B-cell tolerance and autoimmune disease (2014) Müller J, Nitschke L Journal article, Review article IN VIVO EFFECTS OF EPRATUZUMAB, A MONOCLONAL ANTIBODY TARGETING HUMAN CD22, ON B CELL FUNCTION IN HUMAN CD22 KNOCK-IN (HUKI) MICE (2014) Brandl C, Özgör L, Wöhner M, Shock A, Nitschke L Conference contribution