Lehrstuhl für Genetik

IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions. (2017) Lee CH, Romain G, Yan W, Watanabe M, Charab W, Todorova B, Lee J, et al. Journal article Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease. (2017) Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, et al. Journal article Production of the Cytotoxic Cardenolide Glucoevatromonoside by Semisynthesis and Biotransformation of Evatromonoside by a Digitalis lanata Cell Culture. (2017) Munkert J, Santiago Franco M, Nolte E, Silva IT, Oliveira Castilho R, Ottoni FM, Schneider NFZ, et al. Journal article, Original article DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo (2017) Lehmann C, Baranska A, Heidkamp GF, Heger L, Neubert K, Lühr J, Hoffmann A, et al. Journal article New Human CD22/Siglec-2 Ligands with a Triazole Glycoside. (2017) Prescher H, Schweizer A, Kuhfeldt E, Nitschke L, Brossmer R Journal article Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies. (2017) Van den Hoecke S, Ehrhardt K, Kolpe A, El Bakkouri K, Deng L, Grootaert H, Schoonooghe S, et al. Journal article Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells. (2017) Hartholt RB, Wroblewska A, Herczenik E, Peyron I, ten Brinke A, Rispens T, Nolte MA, et al. Journal article Design, Synthesis, and Biological Evaluation of Small, High-Affinity Siglec-7 Ligands: Toward Novel Inhibitors of Cancer Immune Evasion (2017) Prescher H, Frank M, Guetgemann S, Kuhfeldt E, Schweizer A, Nitschke L, Watzl C, Brossmer R Journal article Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease. (2017) Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann J, et al. Journal article IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM). (2017) Wege AK, Weber F, Kroemer A, Ortmann O, Nimmerjahn F, Brockhoff G Journal article