Interdisziplinäres Zentrum für Klinische Forschung (IZKF)

Nsp16 shields SARS–CoV-2 from efficient MDA5 sensing and IFIT1-mediated restriction (2022) Ruß A, Wittmann S, Tsukamoto Y, Herrmann A, Deutschmann J, Lagisquet J, Enßer A, et al. Journal article An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington’s disease patient neurons (2022) Krach F, Stemick J, Börstler T, Weiss A, Lingos I, Reischl S, Meixner H, et al. Journal article Generation of a homozygous and a heterozygous SNCA gene knockout human-induced pluripotent stem cell line by CRISPR/Cas9 mediated allele-specific tuning of SNCA expression (2022) Schneider Y, Turan S, Koller A, Krumbiegel M, Farrell M, Plotz S, Winkler J, Xiang W Journal article Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons (2022) van den Hurk M, Lau S, Marchetto MC, Mertens J, Stern S, Corti O, Brice A, et al. Journal article Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients (2022) Stern S, Lau S, Manole A, Rosh I, Percia MM, Ben Ezer R, Shokhirev MN, et al. Journal article High-resolution label-free mapping of murine kidney vasculature by raster-scanning optoacoustic mesoscopy: an ex vivo study (2022) Goebel CA, Brown E, Fahlbusch F, Wagner A, Buehler A, Raupach T, Hohmann M, et al. Journal article Guidelines for mouse and human DC generation (2022) Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, et al. Journal article Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling (2022) Gámez Belmonte MdlR, Mahapatro M, Erkert L, Gonzalez Acera M, Naschberger E, Yu Y, Tena-Garitaonaindia M, et al. Journal article, Original article Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H (2022) Schütz M, Müller R, Socher E, Wangen C, Full F, Wyler E, Wong DD, et al. Journal article CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy (2022) Battis K, Florio JB, Mante M, Lana A, Naumann I, Gauer C, Lambrecht V, et al. Journal article