Professur für Stammzell-Modelle seltener neuraler Erkrankungen

ALS-associated VRK1 R321C mutation causes proteostatic imbalance and mitochondrial defects in iPSC-derived motor neurons (2024) Oliveira D, Assoni AF, Alves LM, Sakugawa A, Melo US, Teles e Silva AL, Sertie AL, et al. Journal article SARS-CoV-2 Spike Protein Induces Time-Dependent CTSL Upregulation in HeLa Cells and Alveolarspheres (2024) Bolsinger M, Drobny A, Wilfling S, Reischl S, Krach F, Moritz R, Balta D, et al. Journal article Plasma Neurofilaments: Potential Biomarkers of SPG11-Related Hereditary Spastic Paraplegia (2024) Krumm L, Winkler J, Winner B, Regensburger M Journal article Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients. (2024) Krumm L, Pozner T, Zagha N, Coras R, Arnold P, Tsaktanis T, Scherpelz K, et al. Journal article A reversible state of hypometabolism in a human cellular model of sporadic Parkinson’s disease (2023) Schmidt S, Stautner C, Vu DT, Heinz A, Regensburger M, Karayel O, Trümbach D, et al. Journal article Impact of Microbiome–Brain Communication on Neuroinflammation and Neurodegeneration (2023) Stolzer I, Scherer E, Süß P, Rothhammer V, Winner B, Neurath M, Günther C Journal article, Review article Human Induced Pluripotent Stem Cell-Derived Pericytes as Scalable and Editable Source to Study Direct Lineage Reprogramming Into Induced Neurons (2023) Menon R, Petrucci L, Lohrer B, Zhang J, Schulze M, Schichor C, Winner B, et al. Journal article Scaffold-Based (Matrigel™) 3D Culture Technique of Glioblastoma Recovers a Patient-like Immunosuppressive Phenotype (2023) Braun FK, Rothhammer-Hampl T, Lorenz J, Pohl S, Menevse AN, Vollmann-Zwerenz A, Bumes E, et al. Journal article Pathogenic SCN2A variants cause early-stage dysfunction in patient-derived neurons (2023) Asadollahi R, Delvendahl , Muff R, Tan G, Rodrieguez DG, Turan S, Russo M, et al. Journal article CRISPR/Cas9-mediated generation of hESC lines with homozygote and heterozygote p.R331W mutation in CTBP1 to model HADDTS syndrome. (2023) Akdas EY, Turan S, Guhathakurta D, Ekici AB, Salar S, Lie DC, Winner B, Fejtová A Journal article