Reinhart Koselleck-Projekte
Award year: 2024
Category: Scholarship / Grant
Type: Reinhart Koselleck-Projekte
Awarding organization: Deutsche Forschungsgemeinschaft (DFG)
Many drugs work by binding to specific receptor structures on the surface of cells. One particularly important group of these receptors are known as GPCRs. Many painkillers bind to such GPCRs, however they often not only relieve pain, but also cause undesirable side-effects. They can be addictive or cause drowsiness, meaning that patients are almost unable to lead normal lives. Gmeiner would like to establish an innovative approach, which could be used to identify new lead compounds for drugs. These compounds should bind to many different receptors on the cell surface and have particularly low levels of side-effects.